Patricia Arquette was born in Chicago, Illinois in 1968, to Lewis Arquette, an actor, and Brenda Olivia "Mardi" (née Nowak), who was also involved in the arts and worked as a therapist. She made her film debut as Kristen Parker in Chuck Russell's A Nightmare on Elm Street 3: Dream Warriors (1987). Her notable films include Tony Scott's True Romance (1993), Tim Burton's Ed Wood (1994), David O. Russell's Flirting with Disaster (1996), David Lynch's Lost Highway (1997), Stephen Frears's The Hi-Lo Country (1998), Martin Scorsese's Bringing Out the Dead (1999), Andrew Davis's Holes (2003) and Boyhood (2014) For her performance in Richard Linklater's Boyhood (2014), which was filmed from 2002 until 2014, she received widespread critical praise and won the Academy Award, BAFTA Award, Critics' Choice Award, Golden Globe Award, Independent Spirit Award, Satellite Award, and Screen Actors Guild Award, along with many other critics prizes, for Best Supporting Actress. On television, she played the character Allison DuBois—based on the author and medium Allison DuBois, who claims to have psychic abilities—in the supernatural drama series Medium (2005–11). She won the Primetime Emmy Award for Outstanding Lead Actress in a Drama Series in 2005, from two nominations she received for the role in addition to three Golden Globe Award and Screen Actors Guild Award nominations. Arquette also appeared in the CSI franchise as Avery Ryan, the Deputy Director of the FBI, starring in CSI: Cyber (2015–16).

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