A group of women take on Fox News head Roger Ailes and the toxic atmosphere he presided over at the network. Roger Ailes heads Fox News, the real-life cable television network. The film focuses on newscasters Megyn Kelly, Gretchen Carlson and composite character Kayla Pospisil. Kelly is one of the network's most popular newscasters and is to co-moderate the 2016 Republican debate. On the day of the debate, she becomes sick, but still questions Donald Trump on comments he has made about women and if his temperament is appropriate for a president. In retaliation, Trump tweets insults about her and makes comments on television about her 'anger-menstruating'.