Jesse W. Peretz (born May 19, 1968) is an American film and television director, TV producer and former musician. He first rose to prominence as a bass guitarist and founding member of The Lemonheads, a Cambridge, Massachusetts-based band which formed in 1986. Peretz left the band as a musician shortly before their breakout album, It's a Shame About Ray was released, but stayed on as the band photographer. After leaving The Lemonheads, he began to work extensively as a director, first in short form works such as television commercials and music videos, later transitioning to feature films and television series. Recent work includes the film Our Idiot Brother and the TV series Girls. His most recent project is a feature film adaptation of the Nick Hornby novel Juliet, Naked, which premiered at the 2018 Sundance Film Festival. In 2001 he directed The Chateau, in 2007 The Ex, and in 2011 Our Idiot Brother. He has worked as a producer/director on the HBO show Girls and Showtime's Nurse Jackie. It was announced in 2014 that Peretz would helm an adaptation of the Nick Hornby novel Juliet, Naked, produced by Judd Apatow. Peretz was born in Cambridge, Massachusetts, the son of Anne Devereux (née Labouisse), and publisher Marty Peretz. His father is a descendant of Yiddish-language author I. L. Peretz. His maternal grandparents were Elizabeth Scriven (Clark) and diplomat Henry Richardson Labouisse, Jr. His maternal great-grandfather was art collector and philanthropist Stephen Carlton Clark, who was the son of Alfred Corning Clark and the grandson of inventor Edward C. Clark. His father is Jewish and his mother is Protestant.

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