Amma Asante was born in London in 1969, to Ghanaian parents; her father was an accountant, and her mother ran a deli. She was a childhood friend of model Naomi Campbell whom she met when they were seven years old. Asante attended the Barbara Speake stage school in Acton, London, where she trained in dance and drama. She began her film and television career as a child actress, appearing as a regular in the British school drama Grange Hill. She appeared in the "Just Say No" campaign of the 1980s and was one of nine Grange Hill children to take it to the Reagan White House. She gained credits in other British television series, including Desmond's and Birds of a Feather , and was a Children's Channel presenter for a year.

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