Andrew W. Marlowe graduated from Columbia University with a degree in English Literature, and attended the University of Southern California where he obtained his MFA in Screenwriting. He won the Nicholl Fellowship award for screenwriting for his script The Lehigh Pirates. Apogee, a space-based adventure he wrote soon after, sold for $500,000. He went on to write Air Force One, End of Days and Hollow Man. He wrote the unproduced scripts Hammer Down, Alien Prison and a Western intended for Harrison Ford and John Woo. He is the creator and executive producer of the ABC TV series Castle, which he also frequently writes. He is working on two film screenplays, Manhunt and a film adaptation of the comic book character Nick Fury. Marlowe lives in Los Angeles with wife and fellow screenwriter Terri Edda Miller; she has two children from her first marriage.

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