Paula Marshall was born June 12, 1964 in Rockville, Maryland. In 1990, Marshall had a guest role as Iris West, the love interest of Flash (Barry Allen) in the pilot episode on the short-lived Flash. In 1991, she guest-starred on Superboy with a young Clark Kent before he called himself Superman, playing the villainous Christina Riley, a woman who is, in secret, a werewolf. In 1995, Marshall starred in the science fiction cult classic W.E.I.R.D. World, directed by William Maloneas, as Dr. Abby O'Reardon, an evil scientist who rejuvenates her boss (and later becomes his mother) and is bent in turning grown men into babies. After a few years in B movies, Marshall gained a role on 1997's Chicago Sons. In the same year, she landed a recurring role on Spin City and starred with Bette Midler and Dennis Farina in the film That Old Feeling, where her character fell in love with one played by Danny Nucci. Marshall is from Rockville, Maryland. She has been married to fellow actor Danny Nucci since 2003, and they have one child. She is the sister of Virginia politician Bob Marshall, who became widely known for proposing a "bathroom bill" (a law that would have limited transgender individuals access to public restrooms of their born gender) before his defeat by transgender candidate Danica Roem in the November 2017 state election. Paula Marshall attributed his defeat to "karma" for his "homophobic" acts.

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