Kristen Cloke was born 2 september 1968 in Van Nuys, California and attended California State University, Northridge. Her first feature film role was the female lead in Megaville (1990), alongside Billy Zane. Cloke's other credits include lead parts in Caged Fear and A Part of the Family. She has also had featured roles in Stay Tuned, Mistress, and The Marrying Man. Cloke's previous television credits include: Winnetka Road as Maybeth, Silk Stalkings as Annie Overstreet, and guest appearances on One West Waikiki, Cheers, Mad About You, Dear John, Murder She Wrote, Quantum Leap and Doogie Howser, MD, and Vengeance Unlimited. In 1995, Cloke's breakout role came as Captain Shane Autumn Vansen on Space: Above and Beyond. As a result of her work as Vansen, a guest role in The X-Files episode "The Field Where I Died" was written for her. Cloke played Melissa Ephesian, a wife of a cult leader and soulmate of FBI Special Agent Fox Mulder; Melissa is thought to have Dissociative Identity Disorder, though it is later revealed that her different personalities correspond to her past lives. She later described the episode as a love letter between herself and producer Glen Morgan, her then fiancé (now husband). In 1996, she won a Daytime Emmy Award nomination for her performance in the ABC Afterschool Special The Long Road Home, in which she played a young wife who has difficulty relating to her husband's son. In 1997-98, she had recurring role as Dr. Lara Means of the Millennium Group on Millennium. On March 17, 2000, Cloke starred as Valerie Lewton in the film, Final Destination.

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