Sarah Wayne Callies was born in La Grange, Illinois, the daughter of Valerie Wayne and David E. Callies, respectively English and Law professors at the University of Hawaii, Manoa. At age one, Callies moved to Honolulu, Hawaii with her family. Throughout her youth, she expressed an interest in acting through participating in various school plays at the independent Punahou School.
She is best known for her portrayals of Sara Tancredi in Fox's Prison Break, Lori Grimes in AMC's The Walking Dead and Katie Bowman in USA Network's Colony.
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