Arthur Carlton Cuse (born March 22, 1959) is an American screenwriter and producer, best known for the American television series Lost, for which he made the Time magazine list of the 100 most influential people in the world in 2010. Cuse is considered a pioneer in transmedia storytelling and is also highly respected amongst his professional peers for his collaborative achievements.

Cuse teamed up with a Harvard classmate, Hans Tobeason, and made a documentary about rowing at Harvard called Power Ten. He convinced actor, writer and fellow Harvard graduate George Plimpton to narrate the film. After graduating, Cuse headed for Hollywood, and worked as an assistant to a studio head, then as a script reader. By working as a reader, he said, he learned screenwriting. In 1984, Cuse took a job working as an assistant producer for Bernard Schwartz and then spent a year and a half working on Sweet Dreams, directed by Karel Reisz, starring Jessica Lange and Ed Harris. He described the experience as his version of film school. Through a friend, David J. Burke, Cuse was hired as a writer on the Michael Mann series Crime Story. In 1986, Cuse wrote two teleplays for the series.

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