Ten years have passed, and Sidney Prescott, who has put herself back together thanks in part to her writing, is visited by the Ghostface Killer. 20 thousand teenagers of the resort town near Lake Victoria are preparing for the celebration of the annual holiday of early summer. But the nocturnal earthquake releases hundreds of thousands of prehistoric piranhas right on the eve of the celebration. The charming sheriff, her police subordinates and Dr. Gorden Reibanks decide to do everything so that the fun holiday of the youth in the lake does not turn into a bloody feast. But piranhas already know the answer to the question - what will win: youth or centuries-old thirst for blood.